WEBVTT 1 00:00:00.130 --> 00:00:02.149 This video describes the Xeomin 2 00:00:03.630 --> 00:00:04.429 (incobotulinumtoxinA) active 3 00:00:04.430 --> 00:00:06.249 ingredient manufacturing process 4 00:00:06.250 --> 00:00:08.229 and removal of complexing proteins 5 00:00:08.230 --> 00:00:10.230 from the active neurotoxin. 6 00:00:34.360 --> 00:00:35.919 line:85% Xeomin's active ingredient is 7 00:00:35.920 --> 00:00:37.259 line:85% derived from Hall-Strain 8 00:00:37.260 --> 00:00:39.179 line:85% Clostridium botulinum serotype 9 00:00:39.180 --> 00:00:41.079 line:85% A. But the difference is 10 00:00:41.080 --> 00:00:43.059 line:85% in how the active neurotoxin is 11 00:00:43.060 --> 00:00:43.859 line:85% purified. 12 00:00:43.860 --> 00:00:45.479 line:85% Through state-of-the-art extract 13 00:00:45.480 --> 00:00:47.779 line:85% technology, the active neurotoxin 14 00:00:47.780 --> 00:00:49.719 line:85% in Xeomin is isolated, using 15 00:00:49.720 --> 00:00:51.299 line:85% the multi-step process of 16 00:00:51.300 --> 00:00:52.959 line:85% chromatography that uniquely 17 00:00:52.960 --> 00:00:54.979 line:85% purifies the molecule, removing 18 00:00:54.980 --> 00:00:57.059 the complexing proteins, leaving 19 00:00:57.060 --> 00:00:58.839 just the active therapeutic 20 00:00:58.840 --> 00:00:59.840 components.