WEBVTT

00:00:00.500 --> 00:00:03.030 line:0%
XEOMIN® (incobotulinumtoxinA)

00:00:03.030 --> 00:00:04.740 line:0%
carries a boxed warning.

00:00:04.740 --> 00:00:06.410 line:0%
As with all neuromodulators,

00:00:06.410 --> 00:00:07.680 line:0%
there is a risk of spread

00:00:07.680 --> 00:00:09.210 line:0%
from the area of injection

00:00:09.210 --> 00:00:10.983 line:0%
and life-threatening symptoms.

00:00:12.470 --> 00:00:14.630
Reconstituting XEOMIN

00:00:14.630 --> 00:00:17.040
You will need a clean workspace,

00:00:17.040 --> 00:00:18.530
your alcohol wipe,

00:00:18.530 --> 00:00:19.730
diluent saline,

00:00:19.730 --> 00:00:21.563 line:0%
and three types of syringes.

00:00:25.950 --> 00:00:27.890
Next, find your XEOMIN vial,

00:00:27.890 --> 00:00:32.100
available in 50, 100, or 200 Unit doses.

00:00:32.100 --> 00:00:34.030
For additional injection information,

00:00:34.030 --> 00:00:37.330
consult section two
in the Prescribing Information.

00:00:37.330 --> 00:00:40.510 line:0%
Select a dose of XEOMIN
and inspect the vial.

00:00:40.510 --> 00:00:43.290 line:0%
XEOMIN is a sterile,
white to off-white powder,

00:00:43.290 --> 00:00:45.060 line:0%
before reconstitution.

00:00:45.060 --> 00:00:47.970 line:0%
Use saline to reconstitute XEOMIN.

00:00:47.970 --> 00:00:49.280 line:0%
Clean the rubber stopper

00:00:49.280 --> 00:00:51.630 line:0%
of both the saline and XEOMIN vial

00:00:51.630 --> 00:00:52.913 line:0%
with an alcohol wipe.

00:00:53.789 --> 00:00:57.810
Important: Do not pry or pop the cap
off of the XEOMIN vial

00:00:57.810 --> 00:00:59.200
as it is vacuum-packed

00:00:59.200 --> 00:01:01.510
and doing so may result in XEOMIN powder

00:01:01.510 --> 00:01:03.920
dispersing into the air.

00:01:03.920 --> 00:01:07.270
Draw the desired volume
of saline into the syringe,

00:01:07.270 --> 00:01:11.260
then vertically insert the needle
into the XEOMIN vial.

00:01:11.260 --> 00:01:13.791
The vacuum within should
draw most of the saline

00:01:13.880 --> 00:01:15.230
into the XEOMIN vial.

00:01:15.230 --> 00:01:16.900
If the vacuum is not present,

00:01:16.900 --> 00:01:19.020
the XEOMIN vial should be discarded.

00:01:19.020 --> 00:01:21.740
Gently inject any remaining saline.

00:01:21.740 --> 00:01:24.150
For diluent volumes and instructions,

00:01:24.150 --> 00:01:26.190 line:0%
including reconstitution of volumes

00:01:26.190 --> 00:01:28.100 line:0%
greater than five milliliters,

00:01:28.100 --> 00:01:31.019 line:0%
consult table 5 in the
Prescribing Information.

00:01:31.746 --> 00:01:33.500
After the needle is removed,

00:01:33.500 --> 00:01:37.137 line:0%
the XEOMIN vial should be swirled
and flipped to mix.

00:01:37.500 --> 00:01:40.067 line:0%
All powder should be
dissolved into the saline.

00:01:40.610 --> 00:01:43.690 line:0%
Reconstituted XEOMIN
should be clear, colorless,

00:01:43.690 --> 00:01:45.860 line:0%
and free of particulate matter.

00:01:45.860 --> 00:01:47.850
Reconstituted XEOMIN should be used

00:01:47.850 --> 00:01:49.880
for only 1 injection session,

00:01:49.880 --> 00:01:52.050
and for 1 patient only.

00:01:52.050 --> 00:01:53.240
To view details on

00:01:53.240 --> 00:01:55.800
intramuscular and intraglandular injection,

00:01:55.800 --> 00:01:57.846
consult the Prescribing Information.

00:01:58.010 --> 00:01:59.971
Reconstituted XEOMIN can be used

00:02:00.018 --> 00:02:02.340
up to 24 hours after dilution

00:02:02.340 --> 00:02:03.810
if stored in a refrigerator

00:02:03.810 --> 00:02:06.203
between 2 to 8 degrees Celsius.

00:02:07.080 --> 00:02:08.890 line:0%
For more information about XEOMIN,

00:02:08.890 --> 00:02:10.890 line:0%
including Important Safety Information

00:02:10.890 --> 00:02:12.210 line:0%
and BOXED WARNING,

00:02:12.210 --> 00:02:14.163 line:0%
visit XEOMIN.com.